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Synonyms

malignancy

American  
[muh-lig-nuhn-see] / məˈlɪg nən si /
Also malignance

noun

plural

malignancies
  1. the quality or condition of being malignant.

  2. malignant character, behavior, action, or the like.

    the malignancies of war.

  3. a malignant tumor.


malignancy British  
/ məˈlɪɡnənsɪ /

noun

  1. the state or quality of being malignant

  2. pathol a cancerous growth

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

  • nonmalignance noun
  • nonmalignancy noun

Etymology

Origin of malignancy

First recorded in 1595–1605; malign(ant) + -ancy

Vocabulary lists containing malignancy

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Mary’s presence is a malignancy, a blight on the name that Sam has worked so hard to build, an identity that’s separate from Mary’s and secure in its solitude.

From Salon • Apr. 24, 2026

But he sure makes the strongest case for being the most malevolent, influential force there, a malignancy that poisons everything he touches.

From Los Angeles Times • Jan. 29, 2026

Nothing in these stories, translated by Megan McDowell, is quite impossible, yet the shadow of numinous malignancy hangs over everything.

From The Wall Street Journal • Oct. 9, 2025

By the time the lecture was over, he knew that he would drop all of his ongoing projects to find the cause of the unusual malignancy.

From New York Times • Mar. 6, 2024

A substance that is not a carcinogen in the ordinary sense may disturb the normal functioning of some part of the body in such a way that malignancy results.

From "Silent Spring" by Rachel Carson