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mandibuloacral dysplasia

(măn-dĭb′yə-lō-ăkrəl)
n.
  1. A hereditary disorder characterized by dental crowding, ulceration and wasting of the skin on the hands and feet, softening and destruction of the bones, and stiff joints.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.