mannosidosis

[ măn′ə-sĭ-dōsĭs ]

n.

An inherited disorder caused by the deficiency of an enzyme necessary for the metabolism of mannose and characterized by mental retardation, kyphosis, and an enlarged tongue, with the accumulation of mannose in the body tissues.

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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.