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Marfan syndrome

American

[mahr-fan, mahr-fan] / ˈmɑr fæn, mɑrˈfæn /

noun

Pathology.

a hereditary disorder characterized by abnormally elongated bones, especially in the extremities, hypermotility of the joints, and circulatory and eye abnormalities.

Etymology

Origin of Marfan syndrome

Named after Antonin Bernard Marfan (1858–1942), French pediatrician, who described it in 1892

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Marfan syndrome, a condition caused by mutations in the FBN1 gene, typically makes people grow taller than average.

From Los Angeles Times • Dec. 11, 2025

But he did want a romantic partner he’d never had, in part because of a genetic disorder called Marfan syndrome that makes traditional dating tough for him.

From Seattle Times • Feb. 13, 2024

He has been left with an abnormally curved spine, one of the prominent symptoms of his condition, Marfan syndrome, a genetic disorder affecting the body's connective tissues.

From BBC • Jan. 1, 2023

The N.B.A. should be further commended for diagnosing Marfan syndrome in Austin at the combine and potentially saving his life.

From New York Times • Jul. 5, 2014

Other genetic diseases that are inherited in this pattern are achondroplastic dwarfism, Marfan syndrome, and Huntington’s disease.

From Textbooks • Jun. 19, 2013

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023