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active centre

British  

noun

  1. Also called: active sitebiochem the region in an enzyme molecule in which the reactive groups that participate in its action are juxtaposed

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Olga Mayans and Jennifer Fleming created a three-dimensional model of its enzyme structure and active centre to understand the reaction pathway.

From Science Daily Nov. 10, 2023

By 1700 Boston had already overtaken Oxford and Cambridge to become the second most active centre of publishing of English books after London.

From BBC Nov. 25, 2013

Of this widespread commotion London was the active centre; and there a judgment of God, called the plague, had, in the year 1625, desolated whole streets.

From The Continental Monthly, Vol. 4, No. 4, October, 1863 Devoted to Literature and National Policy by Various

A great number of masons were trained in Italy, and came from Lombardy, which in the tenth century even was an active centre of civilisation.

From Illuminated Manuscripts by Bradley, John William

Wallingford, six miles above Streatley, is a very ancient town, and has been an active centre for the making of English history. 

From Three Men in a Boat by Jerome, Jerome K. (Jerome Klapka)

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