Showing definitions for mayo

SEE ALSO

Slang dictionary results for mayo

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• mayo
  mayo

  noun

  mayonnaise.
• Mayo
  Mayo

  noun

  Charles Horace, 1865–1939, and his brother William James, 1861–1939, U.S. surgeons.

mayo

¹ American  

[mey-oh] / ˈmeɪ oʊ /

noun

Informal.

1. mayonnaise.

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Mayo ² American  

[mey-oh] / ˈmeɪ oʊ /

noun

1. Charles Horace, 1865–1939, and his brother William James, 1861–1939, U.S. surgeons.

2. a county in NW Connaught province, in the NW Republic of Ireland. 2,084 sq. mi. (5,400 sq. km). Castlebar.

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Mayo ¹ British  

/ ˈmeɪəʊ /

noun

1. a county of NW Republic of Ireland, in NW Connacht province, on the Atlantic: has many offshore islands and several large lakes. County town: Castlebar. Pop: 117 446 (2002). Area: 5397 sq km (2084 sq miles)

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Mayo ² British  

/ ˈmeɪəʊ /

noun

1. a family of US medical practitioners. They pioneered group practice and established (1903) the Mayo Clinic in Rochester, Minnesota. Foremost among them were William Worrall Mayo (1819–1911), his sons William James Mayo (1861–1939) and Charles Horace Mayo (1865–1939), and Charles's son, Charles William Mayo (1898–1968)

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Usage

What else does mayo mean? Typically, mayo is short for mayonnaise, a classic condiment made of oil, vinegar, and egg yolks. When not, it can also be used as offensive language against white people or a slang term for drugs. Content warning: the following article deals with content related to illicit drugs and offensive and disparaging language.

Etymology

Origin of mayo

By shortening; cf. -o

Example Sentences

The swap is simple: use yogurt in place of some or all of the mayo.

From Salon • Apr. 28, 2026

It has a gloss to it, a kind of quiet sheen that standard mayo simply does not.

From Salon • Apr. 14, 2026

The miso mayo is great as a marinade for steak or chicken thighs.

From The Wall Street Journal • Feb. 11, 2026

Its menu includes flavor profiles such as Thai chicken, carne asada and a California Club — a pizza with ingredients you would normally find in a sandwich, including avocado, bacon, mayo and lettuce.

From Los Angeles Times • Dec. 17, 2025

“Let me get honey-glazed on a roll. Lettuce, tomato, mayo, provolone, sweet peppers, oil and vinegar, black pepper, meat and cheese, hot,” I rattled off like naming brothers and sisters I don’t have.

From "The Boy in the Black Suit" by Jason Reynolds