metachromatic leukodystrophy


An inherited metabolic disorder characterized by myelin loss, accumulation of metachromatic lipids in the white matter of the central and peripheral nervous systems, a marked excess of sulfatidates in white matter and in urine, progressive paralysis, and dementia.

Nearby words

  1. metacentric height,
  2. metacercaria,
  3. metachromasia,
  4. metachromatic,
  5. metachromatic body,
  6. metachromatic stain,
  7. metachromatism,
  8. metachromophil,
  9. metachronous,
  10. metachrosis

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.