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major histocompatibility complex: (in mammals) a group of genes located next to or near each other on a specific chromosome, the sixth in humans, most of which encode glycoproteins of highly variable shapes that are expressed on almost all cell surfaces: it plays the dominant role in distinguishing one individual's cells from another's and in determining the histocompatibility of any two individuals.
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British Dictionary definitions for MHC
major histocompatibility complex; a series of genes located on chromosome 6 that code for antigens. They are important in determining histocompatibility
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012