MHC

1. major histocompatibility complex: (in mammals) a group of genes located next to or near each other on a specific chromosome, the sixth in humans, most of which encode glycoproteins of highly variable shapes that are expressed on almost all cell surfaces: it plays the dominant role in distinguishing one individual's cells from another's and in determining the histocompatibility of any two individuals.

MHC

abbreviation

1. major histocompatibility complex; a series of genes located on chromosome 6 that code for antigens. They are important in determining histocompatibility

Example Sentences

This accumulation of succinate led to expression of immune genes in the nucleus and increased the levels of a protein called MHC on the surface of the tumor.

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In turn, elevated levels of MHC made the tumor cells more visible to specialized immune cells called "killer" T cells, which recognize and eliminate cancer cells.

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Mukherjee writes lucid sentences dense with metaphors as pedagogical tools: the cell as “spacecraft”; the cell’s nucleus as “command center”; the genome as “library”; neutrophils, white blood cells crucial to immune response, as “teenage soldiers deployed to battle”; and MHC class 1 molecules on a cell’s surface as “two open halves of a hotdog bun.”

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“By advancing the racist and ethnic stereotype that all Jews are ‘white’ and ‘privileged’ and therefore oppress people of color, faculty members, students and course assignments in the MHC program thereby invoke the classical anti-Semitic trope that Jews possess disproportionate power and influence in society, which they use for nefarious purposes against non-Jews, while also subjecting them to racial stereotypes about ‘whites,’” said the center.

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The MHC has been meeting virtually for months now, yet the MHC’s decision-making authority has not been reinstated.

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