Lose a chance for, fail to achieve, as in Ruth came late to the party and missed out on all the fun, or Trudy missed out on the promotion. [First half of 1900s] Also see lose out, def. 2.
The American Heritage® Idioms Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.