missense

American  

[mis-sens] / ˈmɪsˌsɛns /

adjective

1. Genetics. relating to or being a genetic mutation involving a nucleotide change that alters a codon and results in the substitution of one amino acid for another in the protein.

---

missense Scientific  

/ mĭs′sĕns′ /

1. Relating to a mutation that changes a codon for one amino acid into a codon for a different amino acid.

2. See more at point mutation

---

Example Sentences

See Examples For:

missense

The team then created transgenic flies with the four missense variants found in affected individuals using two different genetic methods.

From Science Daily ● Mar. 14, 2024

The tool's predictions for missense variants across the entire genome are accessible for non-commercial use and analysis at https://itanlab.shinyapps.io/goflof/.

From Science Daily ● Dec. 14, 2023

So when researchers and doctors find a missense mutation they’ve never seen before, it can be difficult to know what to make of it.

From Scientific American ● Sep. 21, 2023

A missense mutation can stop the replication or reading of that strand.

From Textbooks ● Jun. 9, 2022

In total, two frameshift, two nonsense and one missense mutation, combined with a homozygous deletion spanning the coding region were observed.

From Nature ● Jun. 20, 2012