- the production of immunity against the action of a poison by taking the poison in gradually increased doses.
Origin of mithridatism
1850–55; after Mithridates VI, said to have so immunized himself; see -ism
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- immunity to large doses of poison by prior ingestion of gradually increased doses
- Tolerance or immunity to a poison acquired by taking gradually larger doses of it.