[mith-ri-dey-tiz-uh m]

Origin of mithridatism

1850–55; after Mithridates VI, said to have so immunized himself; see -ism
Related formsmith·ri·dat·ic [mith-ri-dat-ik] /ˌmɪθ rɪˈdæt ɪk/, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for mithridatism


  1. immunity to large doses of poison by prior ingestion of gradually increased doses
Derived Formsmithridatic (ˌmɪθrɪˈdætɪk, -ˈdeɪ-), adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

mithridatism in Medicine


  1. Tolerance or immunity to a poison acquired by taking gradually larger doses of it.
Related formsmith′ri•datic (-dătĭk) adj.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.