mixed connective-tissue disease

n.
  1. A disease of the connective tissues, combining features of systemic lupus erythematosus and systemic sclerosis or polymyositis and characterized by the presence of serum antibodies to nuclear ribonucleoprotein.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.