1. the offspring of individuals that differ with respect to a particular gene pair.
  2. Also called monohybrid cross. a genetic cross made to examine the distribution of one specific set of alleles in the resulting offspring.
  1. of or relating to such an offspring.

Origin of monohybrid

First recorded in 1900–05; mono- + hybrid Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for monohybrid


  1. genetics the offspring of two individuals that differ in respect of a single gene
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012