morpholino

/ ˌmɔːfəʊˈliːnəʊ /

noun

1. a type of molecule used in altering the development of genes by preventing the access of other molecules

Word History and Origins

Origin of morpholino¹

C21: from the organic compound morpholine

Example Sentences

An additional trawl through genetic databases and the morpholino literature revealed that 80% of results from published morpholino experiments were not reproducible in genetic mutants2.

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Using this animal model, we have developed an antisense morpholino–based therapy that prevents the pathogenic Lmna splicing, markedly reducing the accumulation of progerin and its associated nuclear defects.

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Writing in the journal Nature Medicine, Sina Bavari and colleagues said the drugs tested are antisense phosphorodiamidate morpholino oligomers, or PMOs, called AVI-6002 and AVI-6003.

Read more on Reuters