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muscular dystrophy

American  

noun

Pathology.
  1. a hereditary disease characterized by gradual wasting of the muscles with replacement by scar tissue and fat, sometimes also affecting the heart.


muscular dystrophy British  

noun

  1. a genetic disease characterized by progressive deterioration and wasting of muscle fibres, causing difficulty in walking

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

muscular dystrophy Scientific  
/ mŭskyə-lərdĭstrə-fē /
  1. Any of a group of inherited progressive muscle disorders caused by a defect in one or more genes that control muscle function and characterized by gradual irreversible wasting of skeletal muscle.


muscular dystrophy Cultural  
  1. A hereditary disease in which the muscles progressively waste away. The disease can be potentially treated through gene therapy.


Etymology

Origin of muscular dystrophy

First recorded in 1865–70

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Sarcopenia is a form of muscular dystrophy associated with aging and is a popular condition for biotech companies that harbor greater goals of reversing or slowing aging to target.

From Slate • Mar. 30, 2026

These conditions account for roughly 10% of inherited diseases, including cystic fibrosis and Duchenne muscular dystrophy.

From Science Daily • Feb. 28, 2026

The only car here that doesn’t have a Ferrari badge is a lime-green 1972 Dino GTS, named after Enzo Ferrari’s son who died of muscular dystrophy at age 24.

From The Wall Street Journal • Feb. 16, 2026

A third patient died in a study examining the efficacy of the therapy with regard to a different disease called limb-girdle muscular dystrophy.

From Barron's • Jan. 26, 2026

There were tiny babies with club feet, children who had paralyzed limbs from polio, adolescents dying from muscular dystrophy.

From "My Life with the Chimpanzees" by Jane Goodall