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muscular dystrophy

American  

noun

Pathology.
  1. a hereditary disease characterized by gradual wasting of the muscles with replacement by scar tissue and fat, sometimes also affecting the heart.


muscular dystrophy British  

noun

  1. a genetic disease characterized by progressive deterioration and wasting of muscle fibres, causing difficulty in walking

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

muscular dystrophy Scientific  
/ mŭs′kyə-lərdĭs′trə-fē /
  1. Any of a group of inherited progressive muscle disorders caused by a defect in one or more genes that control muscle function and characterized by gradual irreversible wasting of skeletal muscle.


muscular dystrophy Cultural  
  1. A hereditary disease in which the muscles progressively waste away. The disease can be potentially treated through gene therapy.


Etymology

Origin of muscular dystrophy

First recorded in 1865–70


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Nunez Landry has muscular dystrophy, uses a power wheelchair, and needs help doing basic tasks such as opening the refrigerator.

From Salon ● Oct. 31, 2026

A really wonderful guy, sort of a self-advocate and kind of a grump, total badass activist who has muscular dystrophy and has a tracheotomy.

From Los Angeles Times ● Aug. 6, 2026

The discovery could guide future research into muscular dystrophy treatments while also offering broader clues about cancer biology.

From Science Daily ● Aug. 2, 2026

The 36-year-old, who has Duchenne muscular dystrophy, says he was told "from the beginning" that he is medically fit to go home.

From BBC ● May 19, 2026

There were tiny babies with club feet, children who had paralyzed limbs from polio, adolescents dying from muscular dystrophy.

From "My Life with the Chimpanzees" by Jane Goodall

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