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muscular dystrophy

American  

noun

Pathology.
  1. a hereditary disease characterized by gradual wasting of the muscles with replacement by scar tissue and fat, sometimes also affecting the heart.


muscular dystrophy British  

noun

  1. a genetic disease characterized by progressive deterioration and wasting of muscle fibres, causing difficulty in walking

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

muscular dystrophy Scientific  
/ mŭs′kyə-lərdĭs′trə-fē /
  1. Any of a group of inherited progressive muscle disorders caused by a defect in one or more genes that control muscle function and characterized by gradual irreversible wasting of skeletal muscle.


muscular dystrophy Cultural  
  1. A hereditary disease in which the muscles progressively waste away. The disease can be potentially treated through gene therapy.


Etymology

Origin of muscular dystrophy

First recorded in 1865–70


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Using a mouse model of Duchenne muscular dystrophy, the researchers removed TRF2 from muscle stem cells and observed a dramatic worsening of the disease.

From Science Daily ● Nov. 13, 2026

Mourkioti and her colleagues are now investigating whether the way muscle stem cells use TRF2 could lead to new treatment strategies for muscular dystrophy.

From Science Daily ● Nov. 13, 2026

Nunez Landry has muscular dystrophy, uses a power wheelchair, and needs help doing basic tasks such as opening the refrigerator.

From Salon ● Oct. 31, 2026

“Every October, USC reduces our health care options, and at this point only the most expensive plan covers my doctors,” said Sanjay Madhav, a Viterbi School of Engineering professor of practice who has muscular dystrophy.

From Los Angeles Times ● Sep. 3, 2026

There were tiny babies with club feet, children who had paralyzed limbs from polio, adolescents dying from muscular dystrophy.

From "My Life with the Chimpanzees" by Jane Goodall

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