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muscular dystrophy

American  

noun

Pathology.
  1. a hereditary disease characterized by gradual wasting of the muscles with replacement by scar tissue and fat, sometimes also affecting the heart.


muscular dystrophy British  

noun

  1. a genetic disease characterized by progressive deterioration and wasting of muscle fibres, causing difficulty in walking

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

muscular dystrophy Scientific  
/ mŭskyə-lərdĭstrə-fē /
  1. Any of a group of inherited progressive muscle disorders caused by a defect in one or more genes that control muscle function and characterized by gradual irreversible wasting of skeletal muscle.


muscular dystrophy Cultural  
  1. A hereditary disease in which the muscles progressively waste away. The disease can be potentially treated through gene therapy.


Etymology

Origin of muscular dystrophy

First recorded in 1865–70

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

This week the agency is trying to sink promising new therapies for late-stage melanoma and Duchenne muscular dystrophy.

From The Wall Street Journal Jul. 28, 2026

Sarcopenia is a form of muscular dystrophy associated with aging and is a popular condition for biotech companies that harbor greater goals of reversing or slowing aging to target.

From Slate Mar. 30, 2026

These conditions account for roughly 10% of inherited diseases, including cystic fibrosis and Duchenne muscular dystrophy.

From Science Daily Feb. 28, 2026

Sarepta Therapeutics rose 6.4% after the biotech said it would report three-year topline data from its phase three study evaluating its gene therapy elevidys, a potential treatment for Duchenne muscular dystrophy.

From Barron's Jan. 26, 2026

There were tiny babies with club feet, children who had paralyzed limbs from polio, adolescents dying from muscular dystrophy.

From "My Life with the Chimpanzees" by Jane Goodall

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