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musculoskeletal

American

[muhs-kyuh-loh-skel-i-tl] / ˈmʌs kjə loʊˈskɛl ɪ tl /

adjective

concerning, involving, or made up of both the muscles and the bones.

the musculoskeletal system.

musculoskeletal British

/ ˌmʌskjʊləʊˈskɛlɪtəl /

adjective

of or relating to the skeleton and musculature taken together

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of musculoskeletal

First recorded in 1940–45; musculo- + skeletal

Vocabulary lists containing musculoskeletal

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

musculoskeletal

Lilly had paid Boston-based Centrexion Therapeutics $47.5 million upfront for the exclusive worldwide rights to the drug, which was being developed for chronic inflammatory, neuropathic, and musculoskeletal pain.

From Barron's ● Jun. 16, 2026

The results suggest that collagen may help maintain certain aspects of musculoskeletal health over time, although the benefits were generally moderate rather than dramatic.

From Science Daily ● Jun. 5, 2026

Research suggests that more than half of golfers will experience a musculoskeletal injury at some point in their playing careers.

From The Wall Street Journal ● Apr. 6, 2026

But then there are the problems with the musculoskeletal system, which, like other systems in the body, evolved to function with Earth’s gravity pulling down on it.

From Slate ● Mar. 1, 2026

Collagen is the most abundant protein in the body, and forms the scaffolding that helps maintain the structural integrity of our skin and musculoskeletal system.

From BBC ● Sep. 27, 2025

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023