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myelofibrosis

American

[mahy-uh-loh-fahy-broh-sis] / ˌmaɪ ə loʊ faɪˈbroʊ sɪs /

noun

Pathology.

the replacement of bone marrow by fibrous tissue, characteristic of leukemia and certain other diseases.

Etymology

Origin of myelofibrosis

First recorded in 1945–50; myelo- + fibrosis

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Further CT and MRI scans revealed an enlarged spleen and, in September 2025, she was diagnosed with myelofibrosis.

From BBC • Jan. 26, 2026

In 2017, my father was diagnosed with Stage IV myelofibrosis, a rare and deadly form of blood cancer.

From Salon • Dec. 6, 2024

Food and Drug Administration has extended the review period for its experimental drug momelotinib, which is designed to treat anaemic patients with a type of bone marrow cancer called myelofibrosis.

From Reuters • Jun. 16, 2023

Scott Matsuda was hit with the formulary problem when his doctor prescribed him a new drug to treat myelofibrosis, a rare type of chronic leukemia.

From New York Times • Feb. 7, 2023

He was diagnosed with myelofibrosis — a rare type of leukemia — 15 years ago, and for the most part had been able to keep it from spreading too quickly.

From Seattle Times • Feb. 15, 2022

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023