myelofibrosis

American  

[mahy-uh-loh-fahy-broh-sis] / ˌmaɪ ə loʊ faɪˈbroʊ sɪs /

noun

Pathology.

1. the replacement of bone marrow by fibrous tissue, characteristic of leukemia and certain other diseases.

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Etymology

Origin of myelofibrosis

First recorded in 1945–50; myelo- + fibrosis

Example Sentences

Sian, 56, said it was "very difficult to be upbeat" after being told last year she needed a stem cell transplant to survive, following a diagnosis of aggressive myelofibrosis.

From BBC • Jan. 26, 2026

In 2017, my father was diagnosed with Stage IV myelofibrosis, a rare and deadly form of blood cancer.

From Salon • Dec. 6, 2024

And since August 2019, when he was diagnosed with primary myelofibrosis, a rare bone marrow cancer, he has felt what he called a fundamental fear most vividly in the mornings.

From New York Times • Dec. 28, 2023

Food and Drug Administration had approved its oral therapy to treat anemia in patients with a type of bone marrow cancer called myelofibrosis.

From Reuters • Sep. 17, 2023

He was diagnosed with myelofibrosis — a rare type of leukemia — 15 years ago, and for the most part had been able to keep it from spreading too quickly.

From Seattle Times • Feb. 15, 2022