nerve growth factor

American  

noun

Biochemistry.

1. a protein that promotes the growth, organization, and maintenance of sympathetic and some sensory nerve cells. NGF

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nerve growth factor British  

noun

1. a polypeptide produced by neurones and their supporting tissues as well as some other tissues that stimulate the growth of neurones

2. any of various related polypeptides that promote the growth of neurones

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Etymology

Origin of nerve growth factor

First recorded in 1965–70

Example Sentences

See Examples For:

nerve growth factor

First, when binding to nerve growth factor, NRP1 increases the local concentration of nerve growth factor that is presented to TrkA, the signaling receptor.

From Science Daily ● Dec. 5, 2024

In the Journal of Clinical Investigation study, the researchers created one such peptide that blocked the ability of nerve growth factor to interact with NRP1, which stopped pain in cellular studies.

From Science Daily ● Dec. 5, 2024

Mast cells release chemicals called nerve growth factor, which drive overgrowth and increase sensitivity of nerves.

From Science Daily ● Mar. 2, 2024

But it would not stop the neurons from recognizing and responding to other pain-inducing molecules generated by injury or inflammation—protons, prostaglandins, and a protein called nerve growth factor, for example.

From Scientific American ● Oct. 10, 2021

Excessive ovarian production of nerve growth factor facilitates development of cystic ovarian morphology in mice and is a feature of polycystic ovarian syndrome in humans.

From Scientific American ● Sep. 5, 2012