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neuropeptide

American  
[noor-oh-pep-tahyd, nyoor-] / ˌnʊər oʊˈpɛp taɪd, ˌnyʊər- /

noun

  1. any of various short-chain peptides, as endorphins, that function as neuromodulators in the nervous system and as hormones in the endocrine system.


neuropeptide British  
/ ˌnjʊərəʊˈpɛptaɪd /

noun

  1. a peptide produced by neural tissue, esp one with hormonal activity

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of neuropeptide

First recorded in 1970–75; neuro- + peptide

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

And could the effect of these be boosted by doses of the chemical messenger oxytocin, a neuropeptide that helps affectionate interactions make us feel better physically and emotionally?

From The Wall Street Journal • Dec. 4, 2025

Interestingly, a similar increase was also observed in the levels of another stress neuropeptide closely related to PACAP, the calcitonin gene-related peptide, or CGRP.

From Science Daily • Dec. 1, 2023

The researchers hypothesize that somewhere back in our distant evolutionary past, a genetic switch in our ancestors’ brain must have sent neuropeptide Y production into overdrive.

From Scientific American • Sep. 11, 2023

Exercise, by up-regulating neuropeptide Y, helps soothe the anxious amygdala, dial down the fear and hyper-vigilance and keep us calmer.

From New York Times • Mar. 30, 2022

A neuropeptide is a neurotransmitter molecule made up of chains of amino acids connected by peptide bonds.

From Textbooks • Jun. 19, 2013