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nicotine

American  
[nik-uh-teen, -tin, nik-uh-teen] / ˈnɪk əˌtin, -tɪn, ˌnɪk əˈtin /

noun

Chemistry.
  1. a colorless, oily, water-soluble, highly toxic, liquid alkaloid, C 1 0 H 1 4 N 2 , found in tobacco and valued as an insecticide.


nicotine British  
/ ˈnɪkəˌtiːn, ˌnɪkəˈtɪnɪk /

noun

  1. a colourless oily acrid toxic liquid that turns yellowish-brown in air and light: the principal alkaloid in tobacco, used as an agricultural insecticide. Formula: C 10 H 14 N 2

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

nicotine Scientific  
/ nĭkə-tēn′ /
  1. A colorless, poisonous compound occurring naturally in the tobacco plant. It is used in medicine and as an insecticide, and it is the substance in tobacco products to which smokers can become addicted. Nicotine is an alkaloid. Chemical formula: C 10 H 14 N 2 .


nicotine Cultural  
  1. A poisonous chemical substance found in the tobacco plant.


Other Word Forms

  • nicotined adjective
  • nicotineless adjective
  • nicotinic adjective

Etymology

Origin of nicotine

From French, dating back to 1810–20; nicotiana, -ine 2

Explanation

Nicotine is a drug that's present in tobacco. People who are addicted to cigarettes are really hooked on nicotine. Nicotine is most commonly known for occurring in tobacco, and therefore in cigarettes. In small amounts, nicotine is a stimulant, although in larger quantities it's considered a poison and is even used in many insecticides. The earliest French root of the word was nicotiane, which comes from the Modern Latin botanical term for the tobacco plant, Nicotiana, named for Jean Nicot, the French ambassador who first brought tobacco from Brazil to France in 1561.

Keep Reading on Vocabulary.com

Vocabulary lists containing nicotine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Carlson and Patel also launched a precious metals company and a nicotine pouch company.

From The Wall Street Journal • Apr. 13, 2026

He co-founded Soylent, a health-foods company, and Lucy, which makes nontobacco nicotine products.

From MarketWatch • Apr. 3, 2026

These offspring were compared with those from a control group whose fathers had not been exposed to nicotine.

From Science Daily • Mar. 15, 2026

Urban Kieran, a podcast host with a Ph.D. in bio-analytical chemistry, is another example of a podcaster pushing nicotine while giving the appearance of being a medical doctor.

From Salon • Jan. 9, 2026

Thus, if nicotine sulphate is applied before rather than after the apple blossoms turn pink one of the important predators is spared, probably because it is still in the egg stage.

From "Silent Spring" by Rachel Carson