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nicotine

American  
[nik-uh-teen, -tin, nik-uh-teen] / ˈnɪk əˌtin, -tɪn, ˌnɪk əˈtin /

noun

Chemistry.
  1. a colorless, oily, water-soluble, highly toxic, liquid alkaloid, C 1 0 H 1 4 N 2 , found in tobacco and valued as an insecticide.


nicotine British  
/ ˈnɪkəˌtiːn, ˌnɪkəˈtɪnɪk /

noun

  1. a colourless oily acrid toxic liquid that turns yellowish-brown in air and light: the principal alkaloid in tobacco, used as an agricultural insecticide. Formula: C 10 H 14 N 2

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

nicotine Scientific  
/ nĭkə-tēn′ /
  1. A colorless, poisonous compound occurring naturally in the tobacco plant. It is used in medicine and as an insecticide, and it is the substance in tobacco products to which smokers can become addicted. Nicotine is an alkaloid. Chemical formula: C 10 H 14 N 2 .


nicotine Cultural  
  1. A poisonous chemical substance found in the tobacco plant.


Other Word Forms

Derived Forms

Etymology

Origin of nicotine

From French, dating back to 1810–20; see origin at nicotiana, -ine 2

Explanation

Nicotine is a drug that's present in tobacco. People who are addicted to cigarettes are really hooked on nicotine. Nicotine is most commonly known for occurring in tobacco, and therefore in cigarettes. In small amounts, nicotine is a stimulant, although in larger quantities it's considered a poison and is even used in many insecticides. The earliest French root of the word was nicotiane, which comes from the Modern Latin botanical term for the tobacco plant, Nicotiana, named for Jean Nicot, the French ambassador who first brought tobacco from Brazil to France in 1561.

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Vocabulary lists containing nicotine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Based on the photos, the items appeared to be from companies like ALP Drifter Nicotine, Footlocker, Epson, DeepCool AI, Renkus-Heinz and Medicube.

From Los Angeles Times • May 1, 2026

“The holdup quite frankly is Marty Makary,” said Richard Burr, the former North Carolina senator who now leads a pro-vaping group, the Coalition for Smarter Regulation of Nicotine.

From The Wall Street Journal • Apr. 17, 2026

February is National Cancer Prevention Month, and Dr. Jon Ebbert, medical director of the Mayo Clinic Nicotine Dependence Center, says it’s never too late to make lifestyle changes that can decrease your risk of cancer.

From Seattle Times • Feb. 22, 2024

Former smoker Mark Oates, 32, founded the Snus and Nicotine Pouch Users Association and agrees regulations should be reviewed.

From BBC • Oct. 30, 2022

In 1891 he made a collection of his lighter papers from the St James's Gazette and published them as My Lady Nicotine.

From Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 3 "Banks" to "Bassoon" by Various

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