nitric oxide
Americannoun
noun
"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012Closer Look
While nitric oxide (NO) was once regarded solely as a poisonous air pollutant, responsible for the formation of photochemical smog and acid rain leading to the destruction of the ozone layer, today it is also appreciated as a molecule essential to human health. Nitric oxide is the first gas discovered to act as a signaling molecule, a transmitter of important signals to cells in various systems of the human body. Even though NO continues to be detrimental to the environment, it was heralded as Science Magazine's Molecule of the Year in 1992, and the Nobel Prize for physiology or medicine was awarded in 1998 to the three scientists who discovered that NO works as a signaling molecule in the cardiovascular system. It is now known that the cells of a blood vessel's inner walls use NO to signal the vessel to relax and dilate, increasing blood flow. Nitroglycerin, whose effectiveness in treating heart problems was once a mystery, is now known to work by releasing NO. NO has a variety of other important biological functions, including destroying bacteria within the immune system and acting as a neurotransmitter.
Etymology
Origin of nitric oxide
First recorded in 1800–10
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
The CPD gene normally produces an enzyme responsible for generating the amino acid arginine, which then helps create nitric oxide, a key neurotransmitter involved in nerve signaling.
From Science Daily
Even substances that don’t look like well-known signals might act as messengers, as scientists learned when it turned out that gases such as nitric oxide can affect organs.
From Science Magazine
The port and the company are currently negotiating Norwegian’s contribution to the project — a welcome gesture given previous years of emitting carbon and sulfur dioxide, nitric oxide and other harmful particulate matter on Seattle’s waterfront.
From Seattle Times
The multiple health benefits of leafy greens are partly because spinach, lettuce and beetroots are brimming with nitrate, which can be reduced to nitric oxide by nitrate-reducing bacteria inside the mouth.
From Salon
The team explains that the high local temperature activates the other active agent, BNN-6, to release nitric oxide molecules that open the channel in the endoplasmic reticulum.
From Science Daily
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