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A major

American  
[ay may-jer] / ˈeɪ ˈmeɪ dʒər /

noun

  1. Music. the key that has A as the tonic or first note of its scale and is represented by a key signature having three sharps.


Example Sentences

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A major focus of Lin's research is the APOE4 gene variant, which is associated with a substantially increased risk of developing Alzheimer's disease later in life.

From Science Daily ● Nov. 6, 2026

A major shift came with the Health Services Act 1980, which encouraged a more active fundraising culture.

From BBC ● Nov. 5, 2026

A major potential source of savings is the labor required for each item.

From MarketWatch ● Oct. 28, 2026

A major processing facility was later destroyed in a fire.

From The Wall Street Journal ● Oct. 23, 2026

A major factor in his leaving physics and developing an interest in biology had been the reading in 1946 of What Is Life? by the noted theoretical physicist Erwin Schrodinger.

From "Double Helix" by James D. Watson

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