A major
Americannoun
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
A major focus of Lin's research is the APOE4 gene variant, which is associated with a substantially increased risk of developing Alzheimer's disease later in life.
From Science Daily ● Nov. 6, 2026
A major shift came with the Health Services Act 1980, which encouraged a more active fundraising culture.
From BBC ● Nov. 5, 2026
A major potential source of savings is the labor required for each item.
From MarketWatch ● Oct. 28, 2026
A major processing facility was later destroyed in a fire.
From The Wall Street Journal ● Oct. 23, 2026
A major factor in his leaving physics and developing an interest in biology had been the reading in 1946 of What Is Life? by the noted theoretical physicist Erwin Schrodinger.
From "Double Helix" by James D. Watson
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Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.