nuclear envelope

1. The double-layered membrane enclosing the nucleus of a eukaryotic cell. The nuclear envelope has pores that allow the passage of materials into and out of the nucleus.

2. Also called nuclear membrane

Example Sentences

They observed that progerin, which first appears near the nuclear envelope, can move into the cell's cytoplasm through a process called nuclear envelope budding.

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Most animal cells undergo 'open' mitosis, in which the nuclear envelope -- the two-layered membrane separating the nucleus from the rest of the cell -- breaks down when cell division begins.

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However, most fungi use a different form of cell division -- called 'closed' mitosis -- in which the nuclear envelope remains intact throughout the division process.

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"We think this research solves the mystery of how DNA double-strand breaks and the nuclear envelope connect for repair in human cells," said Professor Karim Mekhail, co-principal investigator on the study and a professor of laboratory medicine and pathobiology at U of T's Temerty Faculty of Medicine.

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In 2015, Mekhail and collaborators showed how motor proteins deep inside the nucleus of yeast cells transport double-strand breaks to 'DNA hospital-like' protein complexes embedded in the nuclear envelope at the edge of the nucleus.

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