nucleosome

American  

[noo-klee-uh-sohm, nyoo-] / ˈnu kli əˌsoʊm, ˈnju- /

noun

Cell Biology.

1. any of the repeating subunits of chromatin occurring at intervals along a strand of DNA, consisting of DNA coiled around histone.

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nucleosome British  

/ ˈnjuːklɪəˌsəʊm /

noun

1. a repeating structural unit of chromatin that contains DNA and histones

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nucleosome Scientific  

/ no̅o̅′klē-ə-sōm′ /

1. Any of the repeating subunits of chromatin in eukaryotic cells, consisting of a DNA chain coiled around a core of histones.

2. See Note at histone

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Etymology

Origin of nucleosome

First recorded in 1960–65; nucleo- + -some ³

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Example Sentences

See Examples For:

nucleosome

The nucleosome forms a fundamental repeating unit of chromatin.

From Science Daily ● Mar. 7, 2024

Notably, they observed that Spt16, a component of FACT, captures the histones that have been completely stripped off the duplex DNA from the parental nucleosome.

From Science Daily ● Mar. 7, 2024

For polynucleotide synthesis to occur, the transcription machinery needs to move histones out of the way every time it encounters a nucleosome.

From Textbooks ● Jun. 9, 2022

In this first application of single-cell RNA sequencing to a eukaryotic pathogen, Bjrn Kafsack and colleagues determine the transcriptional changes induced by AP2-G, identifying other AP2 transcription factors, histone-modifying enzymes and regulators of nucleosome positioning.

From Nature ● Sep. 24, 2017

A nucleosome is a single, wrapped DNA-histone complex.

From Textbooks ● Jun. 19, 2013

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