oligonucleotide
Americannoun
noun
Etymology
Origin of oligonucleotide
First recorded in 1940–45; oligo- + nucleotide
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Through the acquisition, Novartis is also gaining access to a new class of RNA therapeutics, called antibody oligonucleotide conjugate, with a platform that enables delivering RNA therapy to muscle, UBS says.
From The Wall Street Journal • Oct. 27, 2025
Similarly, a different antisense oligonucleotide linked to BCC10 greatly reduced another gene, Mapt, which encodes the tau protein and is a target for the treatment of Alzheimer's disease and other dementias.
From Science Daily • Nov. 25, 2024
The announcement came a week after drugmakers Biogen and Ionis Pharmaceuticals said they are terminating development of BIIB105, an antisense oligonucleotide for ALS that showed disappointing results in an early-stage clinical study.
From Science Magazine • May 22, 2024
Another genetic approach that is a bit gray around the categorical edges is known as oligonucleotide therapy.
From Scientific American • Oct. 19, 2021
Alternatively, introducing the CRISPR–Cas9 components alongside a donor oligonucleotide complementary to the target locus and harbouring a premature stop codon should favour the generation of null mutations via homology-directed repair.
From Nature • Sep. 19, 2017
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
