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orotic aciduria

n.
  1. An inherited disorder of pyrimidine metabolism characterized by megaloblastic anemia, leukopenia, retarded growth, and the excretion of orotic acid in the urine.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.