Osler's sign

n.
  1. An indication of acute bacterial endocarditis in which small, circumscribed, painful erythematous swellings appear in the skin and the subcutaneous tissues of the hands and feet.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.