P-glycoprotein

American

[pee glahy-koh-proh-teen] / ˈpi ˌglaɪ koʊˈproʊ tin /

Also permeability glycoprotein

noun

Cell Biology. a glycoprotein that pumps xenobiotics and other harmful substances out of cells, with the side effect of preventing uptake of a large number of drugs, especially drugs used in chemotherapy for cancer, by the body's cells. Abbreviation: Pgp, PGP, PgP.

Other Word Forms

Noun Inflected Forms

P-glycoproteins

plural

Example Sentences

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See Examples For:

P-glycoprotein

By limiting the function of P-glycoprotein 1, more daunorubicin remained inside the leukemia cells, increasing the strength of the treatment.

From Science Daily ● Dec. 14, 2025

Instead, forskolin appeared to interfere with P-glycoprotein 1, a protein that cancer cells use to remove chemotherapy drugs.

From Science Daily ● Dec. 14, 2025

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023