p53 gene

Cultural  

1. A gene that is thought to play a role in regulating cell death or apoptosis, in suppressing tumors, in regulating the cell cycle, and in stopping the cell from dividing when the DNA is damaged.

---

Example Sentences

In around 30 percent of all cases of breast cancer, the cancer cells show mutations or losses in the p53 gene.

From Science Daily • Jan. 3, 2024

Another obvious example would be the p53 gene, which is very strongly associated with cancer suppression.

From Scientific American • Jul. 31, 2023

At the completion of this shortened cell cycle, two daughter cells are produced that have inherited the mutated p53 gene.

From Textbooks • Jun. 9, 2022

Researchers tried gene therapy, adding good copies of the p53 gene to cancer cells.

From New York Times • Dec. 22, 2012

Smokers who develop lung cancer, Harris has found, show tiny alterations in the p53 gene that differ from those in nonsmokers.

From Time Magazine Archive