Paget's disease

American  

noun

1. Pathology. a chronic disease characterized by episodic accelerated bone resorption and growth of abnormal replacement bone, causing bone pain, deformation, fractures, and osteosarcoma; osteitis deformans.

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Paget's disease British  

/ ˈpædʒɪts /

noun

1. Also called: osteitis deformans.  a chronic disease of the bones characterized by inflammation and deformation

2. Also called: Paget's cancer.  cancer of the nipple and surrounding tissue

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Paget's disease Scientific  

/ păj′ĭts /

1. A disease, occurring chiefly in the elderly, in which the bones become enlarged and weakened, often resulting in fracture or deformity.

2. A breast cancer manifested by inflammatory changes of the nipple and surrounding skin.

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Etymology

Origin of Paget's disease

1875–80; named after Sir James Paget, who described it

Example Sentences

Begg and his colleagues scanned the composer’s genome for several conditions linked to hearing loss, including Paget’s disease and lupus.

From Scientific American

Some diseases include such as osteoma, rickets, low bone density and osteoporosis, osteomalacia, Paget’s disease of bone, bone and/or joint pain, osteogenesis imperfecta, increased frequency of fractures, deformed bones, chondrodystrophia fetalis, and other bone diseases that are caused by poor nutrition, genetics, or problems with the rate of bone growth.

From Washington Times

Although grateful to be cancer-free, Mr. Riddick has additional health problems, including arthritis and Paget’s disease, which causes bone and joint pain.

From New York Times

The 69-year-old, from Knebworth, in Hertfordshire, has Paget's disease, which causes him severe pain and means he has to walk with a stick.

From BBC

They recommended that the drugs should only be authorized for short-term use in Paget's disease, a bone disorder; for acute bone loss due to sudden immobilization; and for excess calcium in the blood caused by cancer.

From Reuters