Paget's disease

American  

noun

1. Pathology. a chronic disease characterized by episodic accelerated bone resorption and growth of abnormal replacement bone, causing bone pain, deformation, fractures, and osteosarcoma; osteitis deformans.

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Paget's disease British  

/ ˈpædʒɪts /

noun

1. Also called: osteitis deformans.  a chronic disease of the bones characterized by inflammation and deformation

2. Also called: Paget's cancer.  cancer of the nipple and surrounding tissue

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Paget's disease Scientific  

/ păj′ĭts /

1. A disease, occurring chiefly in the elderly, in which the bones become enlarged and weakened, often resulting in fracture or deformity.

2. A breast cancer manifested by inflammatory changes of the nipple and surrounding skin.

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Etymology

Origin of Paget's disease

1875–80; named after Sir James Paget, who described it

Example Sentences

Begg and his colleagues scanned the composer’s genome for several conditions linked to hearing loss, including Paget’s disease and lupus.

From Scientific American • Mar. 23, 2023

Bisphosphonates, drugs that decrease the activity of osteoclasts, are often used in the treatment of Paget’s disease.

From Textbooks • Jun. 19, 2013

Osteoporosis does not have the elevated blood levels of alkaline phosphatase found in Paget’s disease.

From Textbooks • Jun. 19, 2013

Some scientists believe Paget’s disease is due to an as-yet-unidentified virus.

From Textbooks • Jun. 19, 2013

What do you understand by Paget's disease of the nipple?

From Essentials of Diseases of the Skin Including the Syphilodermata Arranged in the Form of Questions and Answers Prepared Especially for Students of Medicine by Stelwagon, Henry Weightman