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pain in the neck

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Also, pain in the ass or butt. A source of annoyance, a nuisance, as in Joan is a real pain in the neck, with her constant complaining, or Jack told his brother to stop being a pain in the ass. The first of these colloquial expressions dates from about 1900 and originated as a euphemism for the two less polite variants.

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The rainy weather could not ________ my elated spirits on my graduation day.
The American Heritage® Idioms Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
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