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palmoplantar keratoderma

(păl′mō-plăntər, -tär′, päl′mō-, pä′mō-)
n.
  1. An inherited disorder in which diffuse or patchy areas of hypertrophy occur symmetrically and bilaterally on the horny layer of the epidermis on the palms and soles.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.