Dictionary.com
Thesaurus.com
Showing results for patient zero. Search instead for patients regain.

patient zero

American  
[pey-shuhnt zeer-oh] / ˈpeɪ ʃənt ˈzɪər oʊ /

noun

  1. Pathology. the first known carrier of infection in an outbreak.

    Public health officials are tracing all contacts of infected patients, trying to work their way back to find patient zero.

  2. the person or thing that is believed to be the point of origin for any spreading effect, status, or event, especially if negative.

    One rowdy new student was patient zero for all kinds of classroom chaos and problem behaviors.


Etymology

Origin of patient zero

First recorded in 1985–90

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

I could not identify the patient zero of the cheese-pull phenomenon, but it was around this time that Chili’s became inescapable on TikTok—everyone stretching cheese as far as they could while praising the Triple Dipper.

From Slate • Aug. 11, 2025

McConaughey appears to be patient zero for testing the theory while living in the middle of the United States.

From Los Angeles Times • Mar. 8, 2024

Michael Gottlieb, the lawyer for Ms Freeman and Ms Moss, said during closing arguments on Thursday that Mr Giuliani was "patient zero" of the misinformation.

From BBC • Dec. 15, 2023

The news reports suggested that one of them could be patient zero.

From New York Times • Jun. 21, 2023

Emile was patient zero in the worst Ebola outbreak the world has ever seen.

From Salon • Feb. 27, 2023