Dictionary.com
Thesaurus.com

pentobarbital

American  
[pen-tuh-bahr-bi-tawl, -tal] / ˌpɛn təˈbɑr bɪˌtɔl, -ˌtæl /

noun

Pharmacology.
  1. a barbiturate, C 1 1 H 1 7 N 2 O 3 , used as a hypnotic and as a sedative.


Etymology

Origin of pentobarbital

1930–35; pent- ( def. ) + -o- + barbital

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The memo also defends the use of lethal injection, calling the drug pentobarbital "the gold standard of lethal injection drugs".

From BBC • Apr. 24, 2026

The department said it has ordered the Bureau of Prisons to reinstate the execution protocol adopted during the first Trump administration, which relies on pentobarbital as the lethal agent.

From The Wall Street Journal • Apr. 24, 2026

The publication also quotes a medical expert who observed that pentobarbital, the single-drug barbiturate used in Black’s execution, “should cause rapid unconsciousness. It sounds like this did not occur.”

From Slate • Aug. 8, 2025

No matter their source and the procedures used to conduct them, many of the pentobarbital executions carried out by the federal and state governments have not gone smoothly.

From Salon • Jan. 21, 2025

When the vet injected the sodium pentobarbital, Neil fluttered her eyes, assumed a nap position, and died.

From "Me Talk Pretty One Day" by David Sedaris

Vocabulary.com logo
by dictionary.com

Look it up. Learn it forever.

Remember "pentobarbital" for good with VocabTrainer. Expand your vocabulary effortlessly with personalized learning tools that adapt to your goals.

Take me to Vocabulary.com