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pentobarbital

American  
[pen-tuh-bahr-bi-tawl, -tal] / ˌpɛn təˈbɑr bɪˌtɔl, -ˌtæl /

noun

Pharmacology.
  1. a barbiturate, C 1 1 H 1 7 N 2 O 3 , used as a hypnotic and as a sedative.


Etymology

Origin of pentobarbital

1930–35; pent- ( def. ) + -o- + barbital

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The memo also defends the use of lethal injection, calling the drug pentobarbital "the gold standard of lethal injection drugs".

From BBC • Apr. 24, 2026

The Justice Department’s 52-page report found the use of pentobarbital to carry out death sentences is consistent with the Eighth Amendment.

From The Wall Street Journal • Apr. 24, 2026

It also noted, “Whether the pentobarbital had not worked as intended or the implanted heart device repeatedly shocked Black as predicted was not clear.”

From Slate • Aug. 8, 2025

Regarding the question of whether executions with pentobarbital are painful, the department’s review was less definitive in its conclusions than the lawyers and investigators cited above.

From Salon • Jan. 21, 2025

When the vet injected the sodium pentobarbital, Neil fluttered her eyes, assumed a nap position, and died.

From "Me Talk Pretty One Day" by David Sedaris