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pepsinogen

American  
[pep-sin-uh-juhn, -jen] / pɛpˈsɪn ə dʒən, -ˌdʒɛn /

noun

Biochemistry.
  1. crystals, occurring in the gastric glands, that during digestion are converted into pepsin.


pepsinogen British  
/ pɛpˈsɪnədʒən /

noun

  1. the inactive precursor of pepsin produced by the stomach

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of pepsinogen

First recorded in 1875–80; pepsin + -o- + -gen

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

This protects the chief cells, because pepsinogen does not have the same enzyme functionality of pepsin.

From Textbooks • Jun. 9, 2022

Pepsin is secreted by the chief cells in the stomach in an inactive form called pepsinogen.

From Textbooks • Jun. 9, 2022

Hydrochloric acid helps to convert the inactive pepsinogen to pepsin.

From Textbooks • Jun. 9, 2022

Pepsin breaks peptide bonds and cleaves proteins into smaller polypeptides; it also helps activate more pepsinogen, starting a positive feedback mechanism that generates more pepsin.

From Textbooks • Jun. 9, 2022

HCl is necessary for the conversion of pepsinogen to pepsin.

From Textbooks • Jun. 19, 2013

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