pharmacodynamics

[fahr-muh-koh-dahy-nam-iks]

noun

(used with a singular verb)

1. the branch of pharmacology dealing with the course of action, effect, and breakdown of drugs within the body.

pharmacodynamics

/ ˌfɑːməkəʊdaɪˈnæmɪks /

noun

1. (functioning as singular) the branch of pharmacology concerned with the action of drugs on the physiology or pathology of the body

Other Word Forms

• pharmacodynamic adjective
• pharmacodynamical adjective

Word History and Origins

Origin of pharmacodynamics¹

First recorded in 1835–45; pharmaco- + dynamics

Example Sentences

“The maternal cardiovascular system is different, as well as the hemodynamics, the immunology and the pharmacodynamics.”

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Luther and colleagues’ chimaeras are at a more advanced stage of development, because, as the authors show, they have potent in vivo activity as well as favourable toxicity, pharmacokinetics and pharmacodynamics in animal models.

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Healing of pathology may also be compromised in this adverse environment given the immune dysregulation, increased steroid stress hormones, heightened microbial virulence and altered drug pharmacodynamics in space.

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Such studies are becoming more and more common, EMA writes; for instance, the trial in Rennes included subtrials using single and multiple dose administration, as well as trials on drug interactions with food and on pharmacodynamics, the study of a drug’s biochemical and physiologic effects on the body.

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Many of the actionable pharmacogenes that have been identified to date exert a strong effect on the pharmacokinetics or pharmacodynamics of their associated drug, which make them easy to identify.

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