pharmacodynamics

American  

[fahr-muh-koh-dahy-nam-iks] / ˌfɑr mə koʊ daɪˈnæm ɪks /

noun

(used with a singular verb)

1. the branch of pharmacology dealing with the course of action, effect, and breakdown of drugs within the body.

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pharmacodynamics British  

/ ˌfɑːməkəʊdaɪˈnæmɪks /

noun

1. (functioning as singular) the branch of pharmacology concerned with the action of drugs on the physiology or pathology of the body

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Other Word Forms

• pharmacodynamic adjective
• pharmacodynamical adjective

Etymology

Origin of pharmacodynamics

First recorded in 1835–45; pharmaco- + dynamics

Example Sentences

“The maternal cardiovascular system is different, as well as the hemodynamics, the immunology and the pharmacodynamics.”

From Scientific American

Luther and colleagues’ chimaeras are at a more advanced stage of development, because, as the authors show, they have potent in vivo activity as well as favourable toxicity, pharmacokinetics and pharmacodynamics in animal models.

From Nature

Healing of pathology may also be compromised in this adverse environment given the immune dysregulation, increased steroid stress hormones, heightened microbial virulence and altered drug pharmacodynamics in space.

From Scientific American

Such studies are becoming more and more common, EMA writes; for instance, the trial in Rennes included subtrials using single and multiple dose administration, as well as trials on drug interactions with food and on pharmacodynamics, the study of a drug’s biochemical and physiologic effects on the body.

From Science Magazine

Pharmacogenomics focuses on the identification of genetic variants that influence drug effects, typically through alterations in pharmacokinetics — that is, how the drug is absorbed, distributed, metabolized or eliminated — or pharmacodynamics, by modifying its target or by perturbing the biological pathways that shape a patient's sensitivity to its pharmacological effects.

From Nature