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phosphodiester bond

(fŏs′fō-dī-ĕstər)
n.
  1. The covalent chemical bond that holds together the polynucleotide chains of RNA and DNA by joining a specific carbon in the phosphate group in a sugar having five carbons, such as ribose, to a specific carbon in the hydroxyl group of the five-carbon sugar in the adjacent nucleotide.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.