adjective Slang: Vulgar.
angry or annoyed.
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What does “Indigenous” mean?
Also Slang, p.o.'d [pee-ohd] /ˈpiˈoʊd/ .
Origin of pissed off
First recorded in 1935–40
Words nearby pissed off
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2020