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plasminogen

American  
[plaz-min-uh-juhn, -jen] / plæzˈmɪn ə dʒən, -ˌdʒɛn /

noun

Biochemistry.
  1. the blood substance that when activated forms plasmin.


plasminogen British  
/ plæzˈmɪnədʒən /

noun

  1. biochem a zymogen found in blood that gives rise to plasmin on activation

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of plasminogen

First recorded in 1940–45; plasmin + -o- + -gen

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

And scientists at Beth Israel Deaconess Medical Center have begun enrolment for a clinical trial to evaluate an even more powerful clot-busting medication called tissue plasminogen activator, or tPA.

From Nature • May 7, 2020

The patient was still within the three-hour window from his first symptom, and the ER staff put him on the clot-busting treatment known as tissue plasminogen activator, or tPA.

From US News • Jul. 8, 2015

He had to decide whether or not to give her the tissue plasminogen activator or tPA shot, which would break up the clot from her ischemic stroke and restore blood flow to her brain.

From Washington Times • May 11, 2015

Tissue plasminogen activator is an enzyme that catalyzes the conversion of plasminogen to plasmin, the primary enzyme that breaks down clots.

From Textbooks • Jun. 19, 2013

Together he and Folkman eventually determined that various segments of a naturally occurring protein called plasminogen seemed to do the trick.

From Time Magazine Archive

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