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polymerase

American  
[pol-uh-muh-reys, -reyz] / ˈpɒl ə məˌreɪs, -ˌreɪz /

noun

Biochemistry.
  1. any of several enzymes that catalyze the formation of a long-chain molecule by linking smaller molecular units, as nucleotides with nucleic acids.


polymerase British  
/ pəˈlɪməreɪz /

noun

  1. any enzyme that catalyses the synthesis of a polymer, esp the synthesis of DNA or RNA

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

polymerase Scientific  
/ pə-lĭmə-rās′,pŏlə-mə-rās′ /
  1. Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of sequences of DNA or RNA using an existing strand of DNA or RNA as a template.


Etymology

Origin of polymerase

First recorded in 1955–60; polymer + -ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

This interaction blocks gene transcription and interferes with the activity of RNA polymerase or transcription factors.

From Science Daily • May 1, 2026

Now, a team of international scientists, including University of Michigan researchers, have used advanced microscopy to image how ribosomes recruit to mRNA while it's being transcribed by an enzyme called RNA polymerase, or RNAP.

From Science Daily • Nov. 28, 2024

According to testing records, the initial sample of store-bought raw milk carried high levels of the virus, and was found to have a polymerase chain reaction cycle threshold — or Ct — of roughly 25.

From Los Angeles Times • Nov. 27, 2024

However, in the current scenario, the emerging bovine H5N1 strain that has infected American dairy cattle has undergone a specific adaptation in an enzyme called polymerase.

From Salon • Apr. 18, 2024

Once the unwinding is under way, a remarkable enzyme called DNA polymerase helps ensure that the copying works almost perfectly.

From "Cosmos" by Carl Sagan

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