polymerase

American  

[pol-uh-muh-reys, -reyz] / ˈpɒl ə məˌreɪs, -ˌreɪz /

noun

Biochemistry.

1. any of several enzymes that catalyze the formation of a long-chain molecule by linking smaller molecular units, as nucleotides with nucleic acids.

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polymerase British  

/ pəˈlɪməreɪz /

noun

1. any enzyme that catalyses the synthesis of a polymer, esp the synthesis of DNA or RNA

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polymerase Scientific  

/ pə-lĭm′ə-rās′,pŏl′ə-mə-rās′ /

1. Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of sequences of DNA or RNA using an existing strand of DNA or RNA as a template.

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Etymology

Origin of polymerase

First recorded in 1955–60; polymer + -ase

Example Sentences

RNA polymerase II, also called Pol II, is the enzyme responsible for transcribing protein-coding genes in eukaryotic cells.

From Science Daily • Dec. 1, 2025

According to testing records, the initial sample of store-bought raw milk carried high levels of the virus, and was found to have a polymerase chain reaction cycle threshold — or Ct — of roughly 25.

From Los Angeles Times • Nov. 27, 2024

However, in the current scenario, the emerging bovine H5N1 strain that has infected American dairy cattle has undergone a specific adaptation in an enzyme called polymerase.

From Salon • Apr. 18, 2024

Samples were screened for corallicolid infection using polymerase chain reaction -- a laboratory nucleic acid amplification technique -- and sequencing of nuclear small subunit rRNA.

From Science Daily • Apr. 11, 2024

There is a recursion here that is worth noting: like all proteins, DNA polymerase, the enzyme that enables DNA to replicate, is itself the product of a gene.*

From "The Gene" by Siddhartha Mukherjee