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Poxviridae

(pŏks-vîrĭ-dē′)
n.
  1. A family of large complex DNA viruses, including the vaccinia and variola viruses, that are pathogenic to humans and animals and have an affinity for skin tissue.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.