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Synonyms

predispose

American  
[pree-di-spohz] / ˌpri dɪˈspoʊz /

verb (used with object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give an inclination or tendency to beforehand; make susceptible.

    Genetic factors may predispose human beings to certain metabolic diseases.

    Synonyms:
    prepare, prearrange
  2. to render subject, susceptible, or liable.

    The evidence predisposes him to public censure.

  3. to dispose beforehand.

    Synonyms:
    incline, bias
  4. Archaic. to dispose of beforehand, as in a will, legacy, or the like.


verb (used without object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give or furnish a tendency or inclination.

    an underground job that predisposes to lung infection.

predispose British  
/ ˌpriːdɪˈspəʊz /

verb

  1. to incline or make (someone) susceptible to something beforehand

  2. law to dispose of (property, etc) beforehand; bequeath

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Etymology

Origin of predispose

First recorded in 1640–50; pre- + dispose

Explanation

Predispose means to have a tendency toward something. Some people believe that just being born in Canada will predispose you to love ice hockey. Many situations or events can predispose you to have a particular reaction, opinion, or feeling. Being bitten by a dog as a child could predispose you to having a fear of dogs. Having ancestors with great athletic ability might predispose you to enjoy running. If you want to predispose your father to liking your new boyfriend, be sure to tell him about volunteering at the food bank and leave out the bits about his arrest and dropping out of school.

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Vocabulary lists containing predispose

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Research by UC San Francisco’s Sharon suggests migraine headaches predispose people to BPPV, by causing crystals to dislodge from their normal location.

From The Wall Street Journal Apr. 15, 2026

"The whole team undertakes a standardized warm-up that addresses a number of physical concerns that predispose our female athletes to ACLs," she said.

From BBC Jun. 30, 2025

Their goal was to pinpoint what biological conditions might predispose some people to the problem.

From Los Angeles Times Mar. 12, 2025

Nothing in her environment would predispose her to cancer, except for being in close proximity to the fires.

From Slate Jan. 16, 2025

Attitudes such as these certainly predispose one to innumeracy.

From "Innumeracy: Mathematical Illiteracy and Its Consequences" by John Allen Paulos

Nor does it hurt that the extraordinary popularity of the Harry Potter movies predisposes much of the audience to sympathy and affection.

From The Wall Street Journal Mar. 13, 2026

Studies show that adding sugar to any food for babies or small children predisposes them to having a sweet tooth.

From Salon Apr. 25, 2024

This predisposes them to developing the disease but in itself is not symptomatic.

From Science Daily Apr. 22, 2024

People with two copies of the APOE4 gene, which predisposes to Alzheimer’s, may be at higher risk of ARIA.

From Science Magazine Jan. 6, 2023

As a matter of fact, the anticipation of pain due to the dread of it predisposes the part to be much more sensitive than it was before.

From Health Through Will Power by James J. (James Joseph) Walsh

Certain breeds are predisposed to heart or orthopedic issues, for example, that can be expensive to treat.

From MarketWatch Sep. 15, 2026

Among participants assigned to the low-carb diet, those who were genetically predisposed to higher LDL cholesterol were more likely to experience an increase.

From Science Daily Aug. 26, 2026

What's more, With Love, Meghan was never going to change opinions of those who are already, for whatever reason, predisposed against her - just as her new podcast series is unlikely to.

From BBC Apr. 6, 2025

Wojcicki said inquiries poured into 23andMe in 2015 after actor Angelina Jolie disclosed that she’d undergone a precautionary double mastectomy upon learning she carried a gene that predisposed her to breast cancer.

From Los Angeles Times Mar. 26, 2025

My mother had a superstition, in fact, that children were predisposed to certain dangers on certain days, all depending on their Chinese birthdate.

From "The Joy Luck Club" by Amy Tan

“Inadequate nutrition, particularly vitamin A deficiency, can impair the lining of the digestive tract, predisposing birds to inflammation and secondary illness.”

From Los Angeles Times Apr. 20, 2026

Selenium itself is an oxidant, but in low doses it activates responses in a controlled manner, predisposing the body to better defense.

From Science Daily Oct. 30, 2023

But a recent study suggested that the risk of so-called long COVID-19 is highest among people with one of four predisposing factors, including Type 2 diabetes and the presence of autoantibodies.

From Seattle Times Feb. 4, 2022

Many species of Sorbus have a small population size, predisposing them to threatening events.

From BBC Sep. 26, 2021

Was there anything about the Chinese environment predisposing toward Confucian philosophy and cultural conservatism, which may also have profoundly affected history?

From "Guns, Germs, and Steel: The Fates of Human Societies" by Jared M. Diamond

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