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Synonyms

predispose

American  
[pree-di-spohz] / ˌpri dɪˈspoʊz /

verb (used with object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give an inclination or tendency to beforehand; make susceptible.

    Genetic factors may predispose human beings to certain metabolic diseases.

    Synonyms:
    prepare, prearrange
  2. to render subject, susceptible, or liable.

    The evidence predisposes him to public censure.

  3. to dispose beforehand.

    Synonyms:
    incline, bias
  4. Archaic. to dispose of beforehand, as in a will, legacy, or the like.


verb (used without object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give or furnish a tendency or inclination.

    an underground job that predisposes to lung infection.

predispose British  
/ ˌpriːdɪˈspəʊz /

verb

  1. to incline or make (someone) susceptible to something beforehand

  2. law to dispose of (property, etc) beforehand; bequeath

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Etymology

Origin of predispose

First recorded in 1640–50; pre- + dispose


Explanation

Predispose means to have a tendency toward something. Some people believe that just being born in Canada will predispose you to love ice hockey. Many situations or events can predispose you to have a particular reaction, opinion, or feeling. Being bitten by a dog as a child could predispose you to having a fear of dogs. Having ancestors with great athletic ability might predispose you to enjoy running. If you want to predispose your father to liking your new boyfriend, be sure to tell him about volunteering at the food bank and leave out the bits about his arrest and dropping out of school.

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Vocabulary lists containing predispose

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Research by UC San Francisco’s Sharon suggests migraine headaches predispose people to BPPV, by causing crystals to dislodge from their normal location.

From The Wall Street Journal ● Apr. 15, 2026

"The whole team undertakes a standardized warm-up that addresses a number of physical concerns that predispose our female athletes to ACLs," she said.

From BBC ● Jun. 30, 2025

Nothing in her environment would predispose her to cancer, except for being in close proximity to the fires.

From Slate ● Jan. 16, 2025

Researchers are currently focused on understanding the underlying biological pathways leading to long COVID, along with potential biological markers that predispose some individuals to long COVID.

From Salon ● Dec. 21, 2024

Attitudes such as these certainly predispose one to innumeracy.

From "Innumeracy: Mathematical Illiteracy and Its Consequences" by John Allen Paulos

The condition turns up in 10% to 20% of people in their 70s, and predisposes them to blood cancer and, surprisingly, heart disease, likely driven by the inflammation these rogue cells provoke.

From The Wall Street Journal ● Apr. 20, 2026

Studies show that adding sugar to any food for babies or small children predisposes them to having a sweet tooth.

From Salon ● Apr. 25, 2024

"On the other hand, if telomeres are too long, it predisposes you to certain types of cancer."

From Science Daily ● Apr. 11, 2024

Few countries in the region even screen for the disease and give affected newborns penicillin as prophylaxis against the infections to which their condition predisposes them, says Ambroise Wonkam, a geneticist at Johns Hopkins University.

From Science Magazine ● Mar. 12, 2023

It is this that predisposes the patient to the development of the condition which seems to be so acute and yet is really only an exacerbation of a chronic condition.

From Psychotherapy by James J. (James Joseph) Walsh

Many Americans are predisposed to think that wealthy people earned their money and that it’s churlish to try to take it away from them.

From Slate ● Nov. 3, 2026

Certain breeds are predisposed to heart or orthopedic issues, for example, that can be expensive to treat.

From MarketWatch ● Sep. 15, 2026

But he was also predisposed to remedies that would not require what he described as “a priori, the sacrifice of the energy value of oil, gas, and coal.”

From Salon ● Jun. 26, 2026

"Exosomes are used to communicate with and activate surrounding cells, and we have now identified a defect in both the production and the quality of exosomes in cells that we know are predisposed to Alzheimer's."

From Science Daily ● Nov. 25, 2025

Charlie and his partners had done this often enough, and had had enough success, to know that the markets were predisposed to underestimating the likelihood of dramatic change.

From "The Big Short" by Michael Lewis

However, the new study indicates that, without simultaneous maternal pulse recording, this method is a significant risk factor predisposing the fetus to labour-related hypoxia and its long-term neurological effects.

From Science Daily ● Jan. 30, 2024

Which predisposing conditions the person was diagnosed with.

From Seattle Times ● Mar. 23, 2022

Many species of Sorbus have a small population size, predisposing them to threatening events.

From BBC ● Sep. 26, 2021

“Climate change is predisposing the fuels into drier conditions,” Stephens said.

From Los Angeles Times ● Oct. 6, 2020

Was there anything about the Chinese environment predisposing toward Confucian philosophy and cultural conservatism, which may also have profoundly affected history?

From "Guns, Germs, and Steel: The Fates of Human Societies" by Jared M. Diamond

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