[ proh-jes-tuh-rohn ]
/ proʊˈdʒɛs təˌroʊn /
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Biochemistry. a hormone, C21H30O2, that prepares the uterus for the fertilized ovum and maintains pregnancy.
Pharmacology. a commercial form of this compound, obtained from the corpus luteum of pregnant sows or synthesized: used in the treatment of dysfunctional uterine bleeding, dysmenorrhea, threatened or recurrent abortion, etc.


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Origin of progesterone

1930–35; blend of progestin and luteosterone (<German Luteosteron, synonymous with progestin, equivalent to Luteo-luteo- (representing corpus luteum) + -steron (see sterol, -one))
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2022

How to use progesterone in a sentence

British Dictionary definitions for progesterone

/ (prəʊˈdʒɛstəˌrəʊn) /

a steroid hormone, secreted mainly by the corpus luteum in the ovary, that prepares and maintains the uterus for pregnancy. Formula: C 21 H 30 O 2Also called: corpus luteum hormone

Word Origin for progesterone

C20: from pro- 1 + ge (station) + ster (ol) + -one
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for progesterone

[ prō-jĕstə-rōn′ ]

A steroid hormone secreted by the corpus luteum and by the placenta, that acts to prepare the uterus for implantation of the fertilized ovum, to maintain pregnancy, and to promote development of the mammary glands.corpus luteum hormone luteohormone progestational hormone
A drug prepared from natural or synthetic progesterone, used in oral contraceptives, hormone replacement therapy, and in the treatment of menstrual and other gynecologic disorders.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Scientific definitions for progesterone

[ prō-jĕstə-rōn′ ]

A steroid hormone that prepares the uterus for pregnancy, maintains pregnancy, and promotes development of the mammary glands. The main sources of progesterone are the ovary and the placenta. Chemical formula: C21H30O2.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.