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progressive vaccinia

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n.
A severe or even fatal form of vaccinia occurring as a complication of smallpox vaccination chiefly in persons with an immunologic deficiency or dyscrasia, characterized by progressive enlargement of the initial and secondary lesions.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

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